ANATOMY OF THE GALLBLADDER

  • ANATOMY OF THE GALLBLADDER

    • The gallbladder is a pear-shaped, hollow organ located beneath the liver.
    • Function: Stores and concentrates bile, which aids in fat digestion.
    • Capacity: ~30-50 mL of bile.

    LOCATION
    • Lies in the gallbladder fossa on the inferior surface of the liver.
    • Positioned between the right and quadrate lobes of the liver.

    PARTS OF THE GALLBLADDER
    • Fundus – Rounded, anterior part that extends beyond the liver’s margin.
    • Body – Main part, lies in contact with the liver.
    • Neck – Narrow, funnel-shaped part leading to the cystic duct.

    o The HARTMANN’S POUCH is a small outpouching near the neck, where gallstones commonly lodge.

    DUCT SYSTEM (BILIARY TRACT)
    • Cystic Duct connects the gallbladder to the common hepatic duct, forming the common bile duct (CBD).
    • The CBD joins the pancreatic duct and drains into the duodenum (ampulla of Vater).
    • The sphincter of Oddi regulates bile flow into the intestine.

    BLOOD SUPPLY AND VENOUS DRAINAGE
    • Arterial Supply:
    o Cystic artery, a branch of the right hepatic artery.
    • Venous Drainage:
    o Cystic veins drain into the portal vein.

    LYMPHATIC DRAINAGE
    • Lymph drains into the cystic lymph node, then to the hepatic and celiac lymph nodes.

    NERVE SUPPLY
    • Parasympathetic (Stimulatory) – Vagus nerve (CN X) → Stimulates bile release.
    • Sympathetic (Inhibitory) – Celiac plexus → Controls gallbladder contractions.
    • Sensory Innervation – Right phrenic nerve, pain refers to the right shoulder.

    CLINICAL CORRELATIONS
    • Gallstones (Cholelithiasis)
    o Hardened deposits of bile components (cholesterol or pigment stones).
    o May block bile flow, causing pain, nausea, and jaundice.

    • Cholecystitis (Gallbladder Inflammation)
    o Commonly due to gallstones blocking the cystic duct.
    o Symptoms: Severe right upper quadrant (RUQ) pain, fever, nausea.

    • Gallbladder Carcinoma
    o Rare but highly aggressive cancer.
    o Associated with chronic gallstone disease.

    • Murphy’s Sign
    o Pain during deep inspiration when palpating the RUQ → Suggests acute cholecystitis.