KUPIPAKWA RASAYANA – SWARNA VANGA

KUPIPAKWA RASAYANA – SWARNA VANGA

CHEMICAL / PHYTOCHEMICAL COMPOSITION

• Main constituent: Swarna Vanga (Tin-based compound)

• Contains purified tin (Sn) in a bhasmika form (Stannum)

• Traces of gold, iron, zinc, copper and other minerals may be present depending on purification

• When prepared via Kupipakwa method, it contains organometallic complexes and oxidized tin particles

• XRD studies show crystalline structure; SEM reveals microfine particles

PHARMACODYNAMICS AND PHARMACOKINETICS (AS PER FORMULATION)

• Pharmacodynamics:
  • Balances Kapha and Pitta dosha
  • Acts as Medhya, Rasayana, Vrushya, Stambhana
  • Exerts neuroprotective, rejuvenative, and spermatogenic effects

• Pharmacokinetics:
  • Absorbed from mucosal linings of stomach and intestines due to nano-size particles
  • Distributed in plasma and tissues, especially to shukradhatu
  • Metabolized in liver, and excreted through bile and urine

THERAPEUTIC PROPERTIES AND MODE OF ACTION IN DIFFERENT INDICATIONS

• Vrushya – Improves semen quality and quantity

• Medhya – Enhances memory and cognitive function

• Stambhana – Useful in spermatorrhea, leucorrhea

• Rasayana – Anti-aging and rejuvenative

• Action Mode:
  • Enhances Shukradhatu through dhatu poshana
  • Acts on Majjadhatu improving memory
  • Reduces excessive Kapha secretion in genital-urinary tract
  • Increases retentive power of semen and fluids

Relevant Shloka (Charaka Samhita)

शुक्रं शुक्रं च जनयेत् बलं बलविवर्धनम्।
रसयः क्षयमपोह्य रसायनगुणान्विताः॥
— चरक संहिता, चि. 1/2

AWASTHANUSARA USES (AS APPLICABLE)

• Shukradhatu Kshaya – As Vrushya Rasayana

• Madhumeha – Controls excessive urination and debility

• Daurbalya – Improves strength and vigor

• Smritinasha / Unmada – As Medhya

• Prameha / Upadansha – Local and systemic use

MATRA (DOSE)

• 30 mg to 125 mg per day in divided doses depending on condition and patient strength

• Maximum dose should not exceed 250 mg per day unless under supervision

ANUPANA (ADJUVANT)

• Madhu (Honey)

• Ghee

• Milk – for Vrushya & Medhya action

• Triphala kwatha – for Rasayana karma

• Guduchi swarasa – in Prameha

PATHYAPATHYA

• Pathya:
  • Easily digestible food
  • Ghee, milk, shatavari, guduchi

• Apathya:
  • Alcohol
  • Spicy and fried food
  • Excessive sexual activity
  • Viruddha ahara like fish + milk

SEVANA KALA (TIME OF ADMINISTRATION)

• Morning on empty stomach preferred for Rasayana and Medhya karma

• After meals if digestive issues or gastric irritation is noted

• In Chikitsa kala: Based on dosha involvement (Kapha – morning, Pitta – noon, Vata – evening)

KALA MARYADA (DURATION OF MEDICATION)

• Short-term: 7–14 days in acute conditions

• Long-term Rasayana therapy: 1–3 months under supervision

• Chronic disorders: Intermittent use with proper assessment

SIDE EFFECTS OF MEDICATION (AS APPLICABLE)

• If properly prepared and administered – Safe and effective

• Overdose / long-term use without monitoring:
  • Gastric irritation
  • Headache
  • Metallic taste
  • Hepatotoxicity in very rare cases

ASHUDDHA / APAKWA PROCESSED COMPLICATIONS

• May cause Vishalakshata (internal ulcers), vomiting, burning sensation

• Symptoms of Dhatukshaya or Garavisha-like toxicity

AVIDHI SEVANAJANYA VYADHI AND THEIR SHANTYUPAYA

• Improper Use:
  • Leads to Udarashoola, Vaman, Daha
  • Symptoms of Rasa-vaha srotodushti

• Shantyupaya:
  • Use of Ghrita, Triphala, Madhuyashti
  • Mrudu Virechana with castor oil
  • Use of antidotes like shankha bhasma, kamdudha rasa

Relevant Shloka (Rasaratna Samuchchaya)

नात्यल्पं नात्यधिकं कालमेकेन योजयेत्।
न दोषं कुर्युः सर्वेऽपि सिद्धयो हितकारिणः॥
— रसार्णव, 5/12

RESEARCH UPDATES AND CLINICAL EVIDENCES

• Clinical trials show improvement in sperm count, motility, and libido

• In vitro studies show antioxidant and anti-inflammatory activity

• Nano-sized particles prepared by Kupipakwa method enhance absorption

• Tin-based preparations shown to have spermatogenic and neurotonic actions

• Studies published in AYU journal and IJARS confirm safety when used in proper dosage

CLASSICAL REFERENCE

• Rasamruta 3/95

सुवर्णवङ्गं तु रसायनं स्मृतं
बलप्रदं मेधकरं च दीपनम्।
कषायतिक्तं मधुरं च वीर्यवान्
प्रमेहनाशं च हितं नराणाम्॥

• AFI Vol-I, Kupipakwa Rasayana No. 15:9
  • Method of preparation, heating pattern, collection procedure specified
  • Emphasis on Mareecha bhavana, and Shodhana with lemon juice